The PTPRC Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to B220, CD45, CD45R, loc, LY5, and PTPRC. This antibody recognizes Human, Mouse, and Rat antigen. The PTPRC Polyclonal Antibody has been validated for the following applications: ELISA, and Immunohistochemistry.
Description
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling